Controlled Assembly of Biocompatible Metallic Nanoaggregates Using a Small Molecule Crosslinker
نویسندگان
چکیده
منابع مشابه
Multifunctional small molecule for controlled assembly of oligomeric nanoparticles and crosslinked polymers.
One multifunctional small molecule can undergo a natural condensation reaction under the control of reducing agent to generate amphiphilic oligomers which quickly self-assemble supramolecular nanoparticles or form crosslinked, reversibly degradable polymers.
متن کاملA biocompatible condensation reaction for controlled assembly of nanostructures in live cells
Through controlled synthesis and molecular assembly, biological systems are able to organize molecules into supramolecular structures that carry out sophisticated processes. Although chemists have reported a few examples of supramolecular assembly in water, the controlled covalent synthesis of large molecules and structures in vivo has remained challenging. Here we report a condensation reactio...
متن کاملAssembly-controlled biocompatible interface on a microchip: strategy to highly efficient proteolysis.
A biocompatible interface was constructed on a microchip by using the layer-by-layer (LBL) assembly of charged polysaccharides incorporating proteases for highly efficient proteolysis. The controlled assembly of natural polyelectrolytes and the enzyme-adsorption step were monitored by using a quartz-crystal microbalance and atomic force microscopy (AFM). Such a multilayer-assembled membrane pro...
متن کاملControlled release of 5-fluorouracil and progesterone from magnetic nanoaggregates
BACKGROUND The potential use of magnetic nanoparticles in biomedical applications has witnessed an exponential growth in recent years. METHODS In this study, we used nanoaggregates of magnetic nanoparticles as carriers for controlled drug delivery. The nanoaggregates are formed due to the presence of the block copolymer of polyethylene oxide-polypropylene oxide (Pluronic F-68) and beta-cyclod...
متن کاملChondroitin Sulfate-Based Biocompatible Crosslinker Restores Corneal Mechanics and Collagen Alignment.
Purpose To evaluate the crosslinking effect of functionalized chondroitin sulfate (CS) in an ex vivo rabbit cornea model. Methods Chondroitin sulfate molecules were chemically modified with the N-hydroxysuccinimide (NHS) group. Enucleated rabbit eyes were crosslinked with 2, 5, or 10 mg/mL CS-NHS solution for 30 or 60 minutes. The CS-NHS penetration, corneal swelling ratio, Young's modulus, a...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Advanced Materials
سال: 2015
ISSN: 0935-9648
DOI: 10.1002/adma.201501602